Control of Influenza A Virus in Swine Calls for Whole-Herd Approach

Introduction
Influenza A virus in swine (IAV-S) is considered to be one of the top 3 diseases threatening productivity in swine herds. IAV-S is hard to control on many farms because it can become endemic from the continuous birth and subsequent exposure of naïve piglets to resident IAV-S or as a result of the arrival of replacement female pigs with new IAV-S.1-4

A whole-herd approach (WHA) has been used successfully as a key strategic approach to controlling porcine reproductive and respiratory syndrome (PRRS) virus infection within a population.5 The goal of WHA is to minimize exposure and maximize immunity of susceptible pigs.6 This approach is equally appropriate for IAV-S and can lead to the reduction or elimination of IAV-S endemicity and the impact of IAV-S in young pigs.


Objectives
of whole-herd
approach


Current IAV-S control
Even with homology of circulating strains, an approach that relies on killed vaccines to protect piglets through the transfer of maternal antibodies offers limited control of IAV-S. Current sow vaccination practices generally fail to control IAV-S transmission and can actually prolong the transmission period. As a result, endemic disease will persist because of continuous circulating IAV-S among young animals.7

Additionally, because transmission continues to be a factor, a control program that depends on vaccination solely of sows does not help to control either antigenic drift or IAV-S diversity.7

Why a whole-herd approach?
WHA aims to target the key at-risk populations primarily responsible for IAV-S transmission and circulation (farrowing units, the gilt development unit, and breeding and gestation barns). WHA leverages practices that decrease young pigs’ exposure to IAV-S, maximize their immunity to IAV-S, and limit the ability of new strains of IAV-S to enter the herd.4,8-10

Implementation of WHA takes advantage of the fact that pigs are born free of IAV-S (ie, there is no vertical transmission from the sow).11 It is imperative to capitalize on this opportunity by creating a window in which these young, naïve pigs can be given a strong foundation for IAV-S control. This control is achieved by following practices that minimize the IAV-S challenge in the farrowing house while simultaneously building broad immunity in the young pig.

Ingelvac Provenza® fits in a whole-herd approach
As an intranasal, live attenuated influenza vaccine for neonatal pigs, Ingelvac Provenza stimulates local mucosal immunity, offering protection at the site of natural IAV-S infection. Ingelvac Provenza provides broad cross-protection against the ever-evolving risk of IAV-S, through the nursery period and beyond.12-14 Only Ingelvac Provenza protects the right animal, at the right time, by the right route—making it the ideal tool to use as part of a WHA.


For more information about WHA for IAV-S control, talk to your Boehringer Ingelheim representative or visit IngelvacProvenza.com.

Disclaimer

WELCOME TO INGELVACPROVENZA.COM

Are you located within the United States of America?
ARE YOU A VETERINARIAN?

This is a required field

This website is an international information resource intended for veterinarians who are interested in information about Ingelvac Provenza® and influenza A virus in swine.

While the Internet serves a global community, the pharmaceutical industry is subject to country-specific regulatory considerations. This means that the registration status and approved product label may not be the same in different countries.

INGELVAC Provenza® IS ONLY CURRENTLY LICENCED IN THE UNITED STATES OF AMERICA. Information on this website is derived from the product label in the USA.

By checking the box below, you are declaring and confirming that you are a veterinarian professional and that you have read and understood this disclaimer.

You must accept the terms and conditions and data policy to enter the website

Ingelvac Provenza is a trademark of Boehringer Ingelheim Vetmedica GmbH. © 2018 Boehringer Ingelheim Vetmedica, Inc.